Developmental Neurotoxicology
addresses a number of basic principles underlying the vulnerability of the
developing nervous system to environmental toxicant exposure. Evidence of
functional alterations, induced at levels of chemical exposure that fail
to produce structural teratological alterations, indicates that the
evaluation of the functional capacity of exposed animals may indeed offer
a sensitive evaluation of developmental toxicity. The contributing authors
discuss the basic principles of development in structure and functional
components and present information covering various methodological
approaches, as well as evidence for the value of examining the developing
nervous system for environmentally induced perturbations. The final
chapter covers how this type of data is used to evaluate human risk
potential.
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